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KMID : 0381920010310040307
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Korean Journal of Microscopy
2001 Volume.31 No. 4 p.307 ~ p.314
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Effects of Safflower (Carthamus tinctorius L.) Seed Powder on Fracture Healing in Rats
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Park Chang-Hyun
Uhm Chang-Sub
Bae Chun-Sik
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Abstract
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Safflower (Carthamus tinctorius L.) is a thistle-like annual plant mainly grown in dry hot climates as an oilseed or birdseed. Traditionally, the oil has mainly been sold in the health food market because it is unsaturated having high linoleic and oleic acid levels. With increased health consciousness in recent years, the oil quality has become a more general health issue. This study was designed to understand whether safflower seed powder has positive effects on the fracture healing in rats. Simple transverse fracture of rat fibula was made with a rotating diamond disc saw. The histologic changes of rats were observed with a scanning electron microscope. The fractured fibulae showed a complete fusion at the fracture site in the 4th to 5th week after a simple transverse fracture. Administration of safflower seed powder facilitated the speed of histologic changes without affecting qualitative changes. These results suggest that safflower seed powder nay have substances that help the fracture healing process.
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KEYWORD
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Fracture, Rat, Safflower seed powder
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